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[[Image:Bad_medicine_small.PNG|200px|left]]'''AD SCAM ALERT''' |
[[Image:Bad_medicine_small.PNG|200px|left]]'''AD SCAM ALERT''' |
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The following "remedies" have been appearing '''again''' in ads on this wiki's pages: |
The following "remedies" have been appearing '''again''' in ads on this wiki's pages: |
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| − | *[http://diabetesindogs.wikia.com/wiki/Alternative_medication_warnings#Four_products.2C_one_chiropractor "Alternative Treatment #6"] |
+ | *[http://diabetesindogs.wikia.com/wiki/Alternative_medication_warnings#Four_products.2C_one_chiropractor "Alternative Treatment #6"] <b>VetIonx</b> |
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| − | <b>VetIonx</b> |
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| − | <b>Petwellbeing</b> |
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[[Image:Humulin_n.jpg|thumb|200px|left|Humulin N, an isophane insulin suspended with protamine.]]Protamines are proteins derived from the sperm or testes of salmon or related fish. They are added<ref>[http://web.archive.org/web/20070210112022/http://www.jcaai.org/pp/anaph_17_protamine.asp Journal Allergy & Clinical Immunology 1998-Protamine]</ref> are added to [[insulin]]s [[NPH]] Neutral Protamine Hagedorn and [[PZI]] protamine zinc to delay their [[absorption]]. |
[[Image:Humulin_n.jpg|thumb|200px|left|Humulin N, an isophane insulin suspended with protamine.]]Protamines are proteins derived from the sperm or testes of salmon or related fish. They are added<ref>[http://web.archive.org/web/20070210112022/http://www.jcaai.org/pp/anaph_17_protamine.asp Journal Allergy & Clinical Immunology 1998-Protamine]</ref> are added to [[insulin]]s [[NPH]] Neutral Protamine Hagedorn and [[PZI]] protamine zinc to delay their [[absorption]]. |
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Revision as of 18:07, 23 January 2010
 The following "remedies" have been appearing again in ads on this wiki's pages:
See our Ad scams 2 page for a complete listing of pages this scammer targets.
See our Ad scams 2 page for a complete listing of pages this scammer targets. | ||
Humulin N, an isophane insulin suspended with protamine.
Protamines are proteins derived from the sperm or testes of salmon or related fish. They are added[1] are added to insulins NPH Neutral Protamine Hagedorn and PZI protamine zinc to delay their absorption.
The difference between isophane/NPH insulins and PZI insulins is the amount of protamine used; there is more in PZI than in NPH/isophane insulins. It's the extra protamine which makes the PZI a slow-acting insulin.
The basis of absorption of any insulins containing protamine[2] is the breakdown of this protein by proteolytic enzymes[3] or proteases in the body. Only after this is accomplished can the insulin itself be absorbed. More protamine in the suspension means insulin absorption will be delayed longer; less protamine means the insulin will act faster.
Protamine, like insulin itself, is a protein. In the case of antibody formation, it is possible that the insulin itself is not the cause of them; the proteins present in the suspension, such as protamine, may be[4]. In this case, changing the type of suspension would solve the problem.
Protamine has other medical uses as well.
See also suspension. 