| Maxirapid CHO | |
|---|---|
| R, Neutral by Polfa Tarchomin | |
| short-acting | |
| Porcine | |
| U80 | none |
Action in dogs:
| |
| Line: | |
| Also known as: Pork R, pork neutral | |
| Similar to: Betasint Porcine Corriente Hypurin Porcine Neutral,[1] Hypurin Pork Regular Iletin II R, Leo Neutral, Pork Actrapid [2] | |
| Use and Handling: | |
| Shelf Life: 36 months | Type: soluble, clear |
| When Opened: 6 weeks room temp. | |
| In Pen: 6 weeks room temp. | |
| Notes: Protect from light and heat Do Not Freeze, Cartridges in use are not to be refrigerated May be used intravenously May be used intramuscularly | |
Maxirapid CHO pork Regular/Normal/Neutral insulin by Polfa Tarchomin.
Maxirapid CHO [3][4] is a short-acting, pork-based insulin made by Polfa Tarchomin. [5] Betasint Porcine Corriente is similar, as is CP Pharma's [6] Hypurin Porcine Neutral/Hypurin Pork Regular.
Eli Lilly's Iletin II R [7] was comparable, as was Novo Nordisk's Pork Actrapid. [8][9][10][11] which was discontinued at the end of December 2007 [12]
As with all R/neutral insulins, regardless of species, nothing has been added to alter the speed or action of the insulin. [13][14]
A short-acting, soluble, non-suspended insulin produced from r-DNA/GE/GM, bovine, or porcine sources. From 1921 to the 1930's when PZI was developed, R was the only kind of insulin available.
While both R/neutral and semilente insulins are considered fast-acting, they differ in a few ways. As above, there's no suspension or buffer [15] in R/neutral; it's totally dissolved and soluble, meaning it can safely be used intravenously. [16]
The very small insulin particles in semilente insulin are suspended by zinc. [15] Semilente is cloudy, has an acetate buffer and cannot be used intravenously.
R/Neutral insulin cannot be reliably mixed with Lente or Ultralente insulins. [17][18] Semilente can; the ratio of 3 parts semilente insulin to 7 parts ultralente insulin produces Lente insulin. [15]
R/Neutral Insulins[]
|
R/Neutral Insulins | |
|---|---|
|
All Short acting |
| Hypurin Bovine Neutral Betasint Bovine Corriente | |
| Hypurin Vet Neutral (No longer produced.) Iletin R (No longer produced.) Insuvet Neutral (No longer produced.) | |
| Iletin I R (No longer produced.) | |
| Hypurin Porcine Neutral Hypurin Pork Regular Maxirapid CHO, Betasint Porcine Corriente | |
| Pork Actrapid (No longer produced.) Iletin II R (No longer produced.) Leo Neutral (No longer produced.) | |
| Actrapid, Huminsulin Normal Humulin C, Humulin R Humulin Regular, Humulina Regular Humuline R, Humuline Regular Humulin S, Insuman Rapid Novolin R, Umuline Rapide Umuline Regular, Winthrop Rapid Humulin ReliOn R | |
| R-DNA | ReliOn/Novolin R (No longer produced.) |
References[]
- ↑ Response to Withdrawal of Novo Porcine Insulin Range. CP/Wockhardt UK.
- ↑ Montgomery, DAD. Modern Insulin and Insulin Therapy. Royal Victoria Hospital-Belfast.
- ↑ Maxirapid CHO. Polfa Tarchomin.
- ↑ Google Translated page for Maxirapid CHO. Polfa Tarchomin.
- ↑ About Polfa Tarchomin. Polfa Tarchomin.
- ↑ Hypurin Porcine Neutral. Wockhardt UK.
- ↑ Iletin II R Discontinuation Notice. US Food and Drug Administration (July 2005).
- ↑ Pork Actrapid Patient Information. Net Doctor.co.uk.
- ↑ Patient Information Leaflet-Pork Actrapid. Novo Nordisk.
- ↑ Prescribing Porcine Insulin.
- ↑ Prescribing Novo Animal Insulin.
- ↑ Pork Actrapid Discontinuation Notice. Novo Nordisk.
- ↑ Hypurin Porcine Neutral Patient Information. Net Doctor.co.uk.
- ↑ Humulin R patient leaflet. Eli Lilly.
- ↑ 15.0 15.1 15.2 DeRuiter, Jack. Insulin Preparations-Regular Insulin. Auburn University. Cite error: Invalid
<ref>tag; name "Auburn" defined multiple times with different content - ↑ Maddison, Jill E.,Page, Stephen W.,Church, David B. (2008). Small Animal Clinical Pharmacology. Saunders Ltd..
- ↑ Deckert, T. (1980). Intermediate-Acting Insulin Preparations: NPH (Isophane) & Lente. Diabetes Care.
Note--in 1980, there were no r-DNA/GE/GM insulins - ↑ Resource Guide 2005-American Diabetes Association
More Information[]
- NACDS-Insulin Chart-Page 2
- Insulin therapy for dogs and cats Dowling, Patricia, September 1995, Canadian Veterinary Journal
A discussion of Iletin insulins. - Insulin pork regular
 |
 |
 |
 |