Canine Diabetes Wiki
FDA Warning Letter to Eli Lilly re: instability of insulin Lispro (Humalog) crystals-10 February 2010
Reuters News story re: Lilly/Humalog Warning Letter-23 February 2010
Humalog 75 25

Humalog Mix 75/25, known also as Humalog Mix 25.

Another name for Eli Lilly's 25% insulin lispro and 75% insulin lispro protamine suspension analog insulin. [1] The 75% fraction that is NPL (Neutral Protamine Lispro) [2] is a suspension of crystals formed by combining insulin lispro and protamine. It's also called Humalog 75/25.

A study of dogs from 1993-1994 using various fractions of Humalog mixes against human NPH/isophane insulin found only minor differences in the use of Humalog Mix as opposed to NPH/isophane insulin. [3]

Analog Insulins: amino acid sequences[]

Analog Insulin pharmacokinetics[]

These are human activity profiles.


More Information[]