Porcine insulin (from pigs) is an exact amino acid match to that of dogs. [2]
It differs from human insulin in one position. At B #30 on the B insulin chain, dogs and pigs have Alanine, while people have Threonine. It differs from bovine in two positions, both on the A insulin chain: pigs have Threonine at A #8 while cows have Alanine. At the #10 position on the A insulin chain, pigs have Isoleucine--cows have Valine.
Though this shows CP Pharma's Hypurin pork insulins, [3] this information would also apply to Novo's Pork Insulatard, Pork Actrapid, and Pork Mixtard 30. [4][5] They can also be applied to compare these to Lilly's former Iletin II R and Iletin II NPH.
These insulins are natural and entirely or partly derived from pork (pig) sources. Only Iletin I R shown on the list below was a mixture of bovine and porcine insulins; it was composed primarily of beef (apx. 85/90%).
This means that they are identical to canine natural insulin, and a bit closer to feline than human insulin is.
Many humans also prefer porcine-based insulins, which are claimed by some to give a clearer warning of impending low blood sugar than the comparable human GE and analog insulins.
Porcine Insulins[]
See also bovine insulins.
References[]
- ↑ Caninsulin-Product Information. Intervet.
- ↑ Caninsulin-Product Information. Intervet.
- ↑ Prescribing Porcine Insulins.
- ↑ Prescribing Novo Animal Insulins.
- ↑ Response To Withdrawal of Novo Porcine Insulins. CP/Wockhardt UK.
More Information[]
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