All Insuvet insulins have been discontinued by Pfizer Animal Health.[1][2] The insulins were made under contract by Wockhardt UK for both Pfizer and for Schering-Plough Animal Health, who owned the brand name earlier. Wockhardt makes the same insulins under their Hypurin brand name.[3]

Switching from Insuvet to Caninsulin

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Insuvet Neutral--U100 bovine R/Neutral fast-acting insulin.

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Insuvet Lente-U100 bovine lente insulin.

Pfizer Animal Health [7][8] produced three U100 bovine insulins available in the UK:

Some UK dogs also use Insuvet, particularly the lente type. Read about Molly, [10] an Old English Sheepdog, who has diabetes and is also blind. Molly lets neither of these things stop her from living life to the fullest.

Schering-Plough Animal Health contracted Wockhardt UK's CP Pharma to produce its Insuvet insulins, [11] It's believed that Pfizer continued the association until the discontinuation of all Insuvet insulins.

Comparing Insuvet insulins with Hypurin insulinsEdit

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Insuvet Protamine Zinc-U100 bovine protamine zinc insulin

For any of you who are using or were interested in the Insuvet insulins, CP Pharma was the actual producer of them [11] under the Insuvet brand name for Schering-Plough Animal Health. CP makes an identical insulin for humans for each of the Insuvet insulins:

Currently marketed Wockhardt Bovine insulins comparable with Insuvet insulins:

Hypurin Bovine Neutral [4] EMC UK product description.[12]

Insuvet Neutral VMD product description [13]

Hypurin Bovine Lente [5] EMC product description.[14]

Insuvet Lente VMD product description [15]

Hypurin Bovine Protamine Zinc [6] EMC UK product description.[16]

Insuvet Protamine Zinc VMD product description[17]

If you are in Canada, your vet may also be able to obtain manufactured beef insulin from the UK for you through Health Canada's Emergency Drug Release program. [18] With it, you are able to receive up to 6 months worth of insulin; a C$ 50.00 fee for the application is required. [19] If permitted, you would then be eligible to import PZI insulins such as Hypurin Bovine Protamine Zinc, as well as other Hypurin bovine or porcine insulins.

The program is similar to Health Canada's Special Access Programme [20] for importing necessary drugs for people.

Wherever you are, the comparable CP Pharma Hypurin insulins should be able to be imported provided you follow the import rules and guidelines for your country of residence. CP Pharma will be glad to assist you if you contact them through their website link on the CP Pharma page.

Recently the US-FDA has dropped their paperwork requirements regarding the importation of non-US approved drugs for animal patients who need them. [21] While 100% bovine protamine zinc insulin is available in the US through compounding pharmacies, there is no source of bovine R/Neutral or bovine Lente. It would appear that the relaxed restrictions would make it easier and quicker for a veterinarian to obtain bovine insulins for a diabetic patient.


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